Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Probable cell adhesion protein. SUBUNIT: Can form trans-heterodimers with PVRL3/nectin-3. Interacts with CD226. Binds with low affinity to TIGIT (By similarity). Receptor for alphaherpesvirus (such as murine HSV) entry into cells. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=Beta; IsoId=P32507-1; Sequence=Displayed; Name=Alpha; IsoId=P32507-2; Sequence=VSP_002630, VSP_002631; TISSUE SPECIFICITY: Brain, spinal cord, spleen, kidney, heart and liver. SIMILARITY: Belongs to the nectin family. SIMILARITY: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. SIMILARITY: Contains 1 Ig-like V-type (immunoglobulin-like) domain. GENE SYNONYMS:Pvrl2 Mph Pvr Pvs. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 530 AA; 57318 MW; 0ED71BFA2B231BBE CRC64;
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biopax3:xref | |
biopax3:displayName |
PVRL2_MOUSE
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biopax3:name |
CD112,
Herpes virus entry mediator B,
Herpesvirus entry mediator B,
HveB,
Murine herpes virus entry protein B,
Nectin-2,
Poliovirus receptor homolog,
Pvrl2,
mHveB
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biopax3:entityFeature | |
biopax3:organism | |
biopax3:sequence |
MARAAVLPPSRLSPTLPLLPLLLLLLQETGAQDVRVRVLPEVRGRLGGTVELPCHLLPPTTERVSQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKDRLSFVRARPETNADLRDATLAFRGLRVEDEGNYTCEFATFPNGTRRGVTWLRVIAQPENHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVKVTCRVEHESFEEPILLPVTLSVRYPPEVSISGYDDNWYLGRSEAILTCDVRSNPEPTDYDWSTTSGVFPASAVAQGSQLLVHSVDRMVNTTFICTATNAVGTGRAEQVILVRESPSTAGAGATGGIIGGIIAAIIATAVAGTGILICRQQRKEQRLQAADEEEELEGPPSYKPPTPKAKLEEPEMPSQLFTLGASEHSPVKTPYFDAGVSCADQEMPRYHELPTLEERSGPLLLGATGLGPSLLVPPGPNVVEGVSLSLEDEEEDDEEEDFLDKINPIYDALSYPSPSDSYQSKDFFVSRAMYV
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biopax3:standardName |
Poliovirus receptor-related protein 2
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