| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. CATALYTIC ACTIVITY: ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine. COFACTOR: Binds 2 divalent ions per subunit. Magnesium or cobalt (By similarity). COFACTOR: Binds 1 potassium ion per subunit (By similarity). PATHWAY: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1. SUBUNIT: Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B). PTM: The alpha' subunit is a post-translationally modified version of MAT2A. SIMILARITY: Belongs to the AdoMet synthase family. GENE SYNONYMS:MAT2A AMS2 MATA2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 395 AA; 43661 MW; 2E7D1B91CC4F7BDD CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:6904,
urn:biopax:RelationshipXref:NCBI GENE_4144,
urn:biopax:RelationshipXref:REFSEQ_NP_005902,
urn:biopax:UnificationXref:UNIPROT_A8K511,
urn:biopax:UnificationXref:UNIPROT_D6W5L1,
urn:biopax:UnificationXref:UNIPROT_P31153,
urn:biopax:UnificationXref:UNIPROT_Q53SP5
|
| biopax3:displayName |
METK2_HUMAN
|
| biopax3:name |
2.5.1.6,
AdoMet synthase 2,
MAT 2,
MAT-II,
MAT2A,
Methionine adenosyltransferase 2,
Methionine adenosyltransferase II
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
|
| biopax3:standardName |
S-adenosylmethionine synthase isoform type-2
|