| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Involved in the presentation of foreign antigens to the immune system. SUBUNIT: Heterodimer of an alpha chain and a beta chain (beta-2- microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. PTM: Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity). POLYMORPHISM: The following alleles of B-44 are known: B*44:02 (B- 12; B44.2), B*44:04, B*44:05, B*44:07, B*44:08 (B44BO), B*44:09, B*44:12 and B*44:13. The sequence shown is that of B*44:02. SIMILARITY: Belongs to the MHC class I family. SIMILARITY: Contains 1 Ig-like C1-type (immunoglobulin-like) domain. GENE SYNONYMS:HLA-B HLAB. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 362 AA; 40481 MW; E45C71FDEFC628AD CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:4932,
urn:biopax:UnificationXref:UNIPROT_P10320,
urn:biopax:UnificationXref:UNIPROT_P30481,
urn:biopax:UnificationXref:UNIPROT_P30482,
urn:biopax:UnificationXref:UNIPROT_P79524,
urn:biopax:UnificationXref:UNIPROT_Q29850,
urn:biopax:UnificationXref:UNIPROT_Q5RIP1,
urn:biopax:UnificationXref:UNIPROT_Q860I4,
urn:biopax:UnificationXref:UNIPROT_Q861B5,
urn:biopax:UnificationXref:UNIPROT_Q9BCM7,
urn:biopax:UnificationXref:UNIPROT_Q9MYC3,
urn:biopax:UnificationXref:UNIPROT_Q9UQS8
|
| biopax3:displayName |
1B44_HUMAN
|
| biopax3:name |
Bw-44,
HLA-B,
MHC class I antigen B*44
|
| biopax3:organism | |
| biopax3:sequence |
MRVTAPRTLLLLLWGAVALTETWAGSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYGCDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVTLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSLTA
|
| biopax3:standardName |
HLA class I histocompatibility antigen, B-44 alpha chain
|