| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. CATALYTIC ACTIVITY: RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2). COFACTOR: FAD. SUBUNIT: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity). SUBCELLULAR LOCATION: Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. MASS SPECTROMETRY: Mass=59474; Mass_error=14.0; Method=Electrospray; Range=2-520; Source=PubMed:11049757; SIMILARITY: Belongs to the flavin monoamine oxidase family. WEB RESOURCE: Name=SHMPD; Note=The Singapore human mutation and polymorphism database; URL="http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=MAOB"; WEB RESOURCE: Name=Wikipedia; Note=Monoamine oxidase entry; URL="http://en.wikipedia.org/wiki/Monoamine_oxidase"; GENE SYNONYMS:MAOB. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 520 AA; 58763 MW; 358D1025F5BCA604 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:6834,
urn:biopax:RelationshipXref:NCBI GENE_4129,
urn:biopax:RelationshipXref:REFSEQ_NP_000889,
urn:biopax:UnificationXref:UNIPROT_B2R6R3,
urn:biopax:UnificationXref:UNIPROT_D3DWC3,
urn:biopax:UnificationXref:UNIPROT_P27338,
urn:biopax:UnificationXref:UNIPROT_Q7Z6S2
|
| biopax3:displayName |
AOFB_HUMAN
|
| biopax3:name |
1.4.3.4,
MAO-B,
MAOB,
Monoamine oxidase type B
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
| biopax3:standardName |
Amine oxidase [flavin-containing] B
|