| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER, AND MASS SPECTROMETRY. SUBUNIT: Interacts with TMEM132A and TRIM21. May form a complex with ERLEC1, OS9, SEL1L and SYVN1 (By similarity). Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with DNAJC1 (via J domain). SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Melanosome (By similarity). SIMILARITY: Belongs to the heat shock protein 70 family. GENE SYNONYMS:Hspa5 Grp78. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 655 AA; 72422 MW; AFB795D15E20FAC2 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:95835,
urn:biopax:RelationshipXref:NCBI GENE_14828,
urn:biopax:RelationshipXref:REFSEQ_NP_001156906,
urn:biopax:RelationshipXref:REFSEQ_NP_071705,
urn:biopax:UnificationXref:UNIPROT_O35642,
urn:biopax:UnificationXref:UNIPROT_P20029,
urn:biopax:UnificationXref:UNIPROT_Q3UFF2,
urn:biopax:UnificationXref:UNIPROT_Q61630
|
| biopax3:displayName |
GRP78_MOUSE
|
| biopax3:name |
BiP,
GRP-78,
Heat shock 70 kDa protein 5,
Hspa5,
Immunoglobulin heavy chain-binding protein
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MMKFTVVAAALLLLGAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGGPPPTGEEDTSEKDEL
|
| biopax3:standardName |
78 kDa glucose-regulated protein
|