| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. SUBUNIT: Interacts with CDCP1. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form. PTM: Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. SIMILARITY: Belongs to the syndecan proteoglycan family. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/SDC1ID42223ch2p24.html"; GENE SYNONYMS:SDC1 SDC. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 310 AA; 32462 MW; 8E9EF4A57F5FDBD0 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:10658,
urn:biopax:RelationshipXref:NCBI GENE_6382,
urn:biopax:RelationshipXref:REFSEQ_NP_001006947,
urn:biopax:RelationshipXref:REFSEQ_NP_002988,
urn:biopax:UnificationXref:UNIPROT_D6W523,
urn:biopax:UnificationXref:UNIPROT_P18827,
urn:biopax:UnificationXref:UNIPROT_Q53QV0,
urn:biopax:UnificationXref:UNIPROT_Q546D3,
urn:biopax:UnificationXref:UNIPROT_Q96HB7
|
| biopax3:displayName |
SDC1_HUMAN
|
| biopax3:name |
CD138,
SDC1,
SYND1
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MRRAALWLWLCALALSLQPALPQIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHLASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
|
| biopax3:standardName |
Syndecan-1
|