Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Transcription factor. SUBUNIT: Interacts with MAF and MAFB (By similarity). Binds to DAXX. Interacts with UBE2I. SUBCELLULAR LOCATION: Nucleus. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=c-ETS-1A; IsoId=P14921-1; Sequence=Displayed; Name=c-ETS-1B; IsoId=P14921-2; Sequence=VSP_001464; Name=3; IsoId=P14921-3; Sequence=VSP_043152; Note=No experimental confirmation available; PTM: Sumoylated on Lys-15 and Lys-227, preferentially by SUMO2; which inhibits transcriptional activity (By similarity). PTM: Ubiquitinated; which induces proteasomal degradation (By similarity). SIMILARITY: Belongs to the ETS family. SIMILARITY: Contains 1 ETS DNA-binding domain. SIMILARITY: Contains 1 PNT (pointed) domain. GENE SYNONYMS:ETS1 EWSR2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 441 AA; 50408 MW; 3B66BCC464B393FB CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:3488,
urn:biopax:RelationshipXref:NCBI GENE_2113,
urn:biopax:RelationshipXref:REFSEQ_NP_001137292,
urn:biopax:RelationshipXref:REFSEQ_NP_001155894,
urn:biopax:RelationshipXref:REFSEQ_NP_005229,
urn:biopax:UnificationXref:UNIPROT_P14921,
urn:biopax:UnificationXref:UNIPROT_Q14278,
urn:biopax:UnificationXref:UNIPROT_Q16080,
urn:biopax:UnificationXref:UNIPROT_Q6N087
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biopax3:displayName |
ETS1_HUMAN
|
biopax3:name |
ETS1,
p54
|
biopax3:entityFeature |
urn:biopax:ModificationFeature:ETS1_HUMAN_1,
urn:biopax:ModificationFeature:ETS1_HUMAN_10,
urn:biopax:ModificationFeature:ETS1_HUMAN_2,
urn:biopax:ModificationFeature:ETS1_HUMAN_3,
urn:biopax:ModificationFeature:ETS1_HUMAN_4,
urn:biopax:ModificationFeature:ETS1_HUMAN_5,
urn:biopax:ModificationFeature:ETS1_HUMAN_6,
urn:biopax:ModificationFeature:ETS1_HUMAN_7,
urn:biopax:ModificationFeature:ETS1_HUMAN_8,
urn:biopax:ModificationFeature:ETS1_HUMAN_9
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biopax3:organism | |
biopax3:sequence |
MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE
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biopax3:standardName |
Protein C-ets-1
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