| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM family. SIMILARITY: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. WEB RESOURCE: Name=Functional Glycomics Gateway - Glycan Binding; Note=ICAM-2; URL="http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Itlect_262"; GENE SYNONYMS:ICAM2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 275 AA; 30654 MW; C54FB34D92A6FC38 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:5345,
urn:biopax:RelationshipXref:NCBI GENE_3384,
urn:biopax:RelationshipXref:REFSEQ_NP_000864,
urn:biopax:RelationshipXref:REFSEQ_NP_001093256,
urn:biopax:RelationshipXref:REFSEQ_NP_001093257,
urn:biopax:RelationshipXref:REFSEQ_NP_001093258,
urn:biopax:RelationshipXref:REFSEQ_NP_001093259,
urn:biopax:UnificationXref:UNIPROT_P13598,
urn:biopax:UnificationXref:UNIPROT_Q14600
|
| biopax3:displayName |
ICAM2_HUMAN
|
| biopax3:name |
CD102,
ICAM-2,
ICAM2
|
| biopax3:organism | |
| biopax3:sequence |
MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
|
| biopax3:standardName |
Intercellular adhesion molecule 2
|