| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Serine hydrolase involved in the detoxification of formaldehyde. CATALYTIC ACTIVITY: S-formylglutathione + H(2)O = glutathione + formate. CATALYTIC ACTIVITY: 4-methylumbelliferyl acetate + H(2)O = 4- methylumbelliferone + acetate. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasmic vesicle. POLYMORPHISM: There are two major electrophoretic isotypes. The sequence of the ESD*1 variant is shown. SIMILARITY: Belongs to the esterase D family. SEQUENCE CAUTION: Sequence=CAI12225.1; Type=Erroneous gene model prediction; Sequence=CAI12226.1; Type=Erroneous gene model prediction; GENE SYNONYMS:ESD. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 282 AA; 31463 MW; BFC20D5FA2BB0DCE CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:3465,
urn:biopax:RelationshipXref:NCBI GENE_2098,
urn:biopax:RelationshipXref:REFSEQ_NP_001975,
urn:biopax:UnificationXref:UNIPROT_P10768,
urn:biopax:UnificationXref:UNIPROT_Q5TBU8,
urn:biopax:UnificationXref:UNIPROT_Q5TBV0,
urn:biopax:UnificationXref:UNIPROT_Q5TBV2,
urn:biopax:UnificationXref:UNIPROT_Q9BVJ2
|
| biopax3:displayName |
ESTD_HUMAN
|
| biopax3:name |
3.1.1.56,
3.1.2.12,
ESD,
Esterase D,
FGH,
Methylumbelliferyl-acetate deacetylase
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA
|
| biopax3:standardName |
S-formylglutathione hydrolase
|