| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
CATALYTIC ACTIVITY: UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. COFACTOR: Binds 1 iron ion per subunit (Potential). COFACTOR: Binds 1 zinc ion per subunit (Potential). PATHWAY: Carbohydrate metabolism; galactose metabolism. SUBUNIT: Homodimer (Probable). DISEASE: Defects in GALT are the cause of galactosemia (GALCT) [MIM:230400]. Galactosemia is an inherited disorder of galactose metabolism that causes jaundice, cataracts, and mental retardation. SIMILARITY: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. WEB RESOURCE: Name=Galt; Note=Galactosemia mutation database; URL="http://www.arup.utah.edu/database/galactosemia/GALT_welcome.php"; WEB RESOURCE: Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/GALT"; GENE SYNONYMS:GALT. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 379 AA; 43363 MW; 99945FF99C4F0066 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:4135,
urn:biopax:RelationshipXref:NCBI GENE_2592,
urn:biopax:RelationshipXref:REFSEQ_NP_000146,
urn:biopax:UnificationXref:UNIPROT_P07902,
urn:biopax:UnificationXref:UNIPROT_Q14355,
urn:biopax:UnificationXref:UNIPROT_Q14356,
urn:biopax:UnificationXref:UNIPROT_Q14357,
urn:biopax:UnificationXref:UNIPROT_Q14358,
urn:biopax:UnificationXref:UNIPROT_Q14359,
urn:biopax:UnificationXref:UNIPROT_Q14360,
urn:biopax:UnificationXref:UNIPROT_Q14361,
urn:biopax:UnificationXref:UNIPROT_Q14363,
urn:biopax:UnificationXref:UNIPROT_Q14364,
urn:biopax:UnificationXref:UNIPROT_Q14365,
urn:biopax:UnificationXref:UNIPROT_Q14369,
urn:biopax:UnificationXref:UNIPROT_Q14370,
urn:biopax:UnificationXref:UNIPROT_Q14371,
urn:biopax:UnificationXref:UNIPROT_Q14372,
urn:biopax:UnificationXref:UNIPROT_Q14373,
urn:biopax:UnificationXref:UNIPROT_Q14374,
urn:biopax:UnificationXref:UNIPROT_Q14375,
urn:biopax:UnificationXref:UNIPROT_Q14377,
urn:biopax:UnificationXref:UNIPROT_Q14378,
urn:biopax:UnificationXref:UNIPROT_Q14380,
urn:biopax:UnificationXref:UNIPROT_Q14381,
urn:biopax:UnificationXref:UNIPROT_Q14382,
urn:biopax:UnificationXref:UNIPROT_Q14383,
urn:biopax:UnificationXref:UNIPROT_Q14384,
urn:biopax:UnificationXref:UNIPROT_Q14385,
urn:biopax:UnificationXref:UNIPROT_Q14386,
urn:biopax:UnificationXref:UNIPROT_Q14387,
urn:biopax:UnificationXref:UNIPROT_Q14389,
urn:biopax:UnificationXref:UNIPROT_Q16766,
urn:biopax:UnificationXref:UNIPROT_Q53XK1,
urn:biopax:UnificationXref:UNIPROT_Q5VZ81,
urn:biopax:UnificationXref:UNIPROT_Q96BY1
|
| biopax3:displayName |
GALT_HUMAN
|
| biopax3:name |
2.7.7.12,
GALT,
Gal-1-P uridylyltransferase,
UDP-glucose--hexose-1-phosphate uridylyltransferase
|
| biopax3:organism | |
| biopax3:sequence |
MSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGAIRANGEVNPQYDSTFLFDNDFPALQPDAPSPGPSDHPLFQAKSARGVCKVMCFHPWSDVTLPLMSVPEIRAVVDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQAYKSQHGEPLLMEYSRQELLRKERLVLTSEHWLVLVPFWATWPYQTLLLPRRHVRRLPELTPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGSEAGANWNHWQLHAHYYPPLLRSATVRKFMVGYEMLAQAQRDLTPEQAAERLRALPEVHYHLGQKDRETATIA
|
| biopax3:standardName |
Galactose-1-phosphate uridylyltransferase
|