| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. SUBUNIT: Heterodimer with Gbeta5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O94810-1; Sequence=Displayed; Name=2; IsoId=O94810-2; Sequence=VSP_023497; SIMILARITY: Contains 1 DEP domain. SIMILARITY: Contains 1 G protein gamma domain. SIMILARITY: Contains 1 RGS domain. GENE SYNONYMS:RGS11. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 467 AA; 52946 MW; 46BEE11D77C2C5F7 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:9993,
urn:biopax:RelationshipXref:NCBI GENE_8786,
urn:biopax:RelationshipXref:REFSEQ_NP_003825,
urn:biopax:RelationshipXref:REFSEQ_NP_899180,
urn:biopax:UnificationXref:UNIPROT_O75883,
urn:biopax:UnificationXref:UNIPROT_O94810,
urn:biopax:UnificationXref:UNIPROT_Q4TT71
|
| biopax3:displayName |
RGS11_HUMAN
|
| biopax3:name |
RGS11
|
| biopax3:organism | |
| biopax3:sequence |
MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQWLAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAELDYAIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVFPFTWRPRHSSPSPALLPTPVEPTAACGPGGGDGVA
|
| biopax3:standardName |
Regulator of G-protein signaling 11
|