| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Involved in the conversion of lanosterol to cholesterol. CATALYTIC ACTIVITY: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3- beta-ol + NADP(+) = 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3- beta-ol + NADPH. SUBCELLULAR LOCATION: Microsome membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi- pass membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O76062-1; Sequence=Displayed; Name=2; IsoId=O76062-2; Sequence=VSP_017898; Note=No experimental confirmation available; TISSUE SPECIFICITY: Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. SIMILARITY: Belongs to the ERG4/ERG24 family. SEQUENCE CAUTION: Sequence=AAC21450.1; Type=Miscellaneous discrepancy; Note=Sequencing errors; Sequence=AAC21457.1; Type=Miscellaneous discrepancy; Note=Sequencing errors; GENE SYNONYMS:TM7SF2 ANG1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 418 AA; 46406 MW; F5618ABE2BF0A911 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11863,
urn:biopax:RelationshipXref:NCBI GENE_7108,
urn:biopax:RelationshipXref:REFSEQ_NP_003264,
urn:biopax:UnificationXref:UNIPROT_A8K4H0,
urn:biopax:UnificationXref:UNIPROT_O76062,
urn:biopax:UnificationXref:UNIPROT_O95982,
urn:biopax:UnificationXref:UNIPROT_Q8IY06,
urn:biopax:UnificationXref:UNIPROT_Q96E64,
urn:biopax:UnificationXref:UNIPROT_Q96GZ1
|
| biopax3:displayName |
ERG24_HUMAN
|
| biopax3:name |
1.3.1.70,
Another new gene 1 protein,
C-14 sterol reductase,
Delta-14-SR,
Putative sterol reductase SR-1,
Sterol C14-reductase,
TM7SF2,
Transmembrane 7 superfamily member 2
|
| biopax3:organism | |
| biopax3:sequence |
MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY
|
| biopax3:standardName |
Delta(14)-sterol reductase
|