| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Necessary for spliceosome assembly. Overexpression causes apoptosis. SUBUNIT: Associates with spliceosomes. Associates with U4/U5/U6 tri-snRNP and with U2 snRNP. SUBCELLULAR LOCATION: Nucleus speckle. Nucleus, Cajal body. Note=Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. TISSUE SPECIFICITY: Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas. DOMAIN: The Tudor domain mediates association with dimethylarginines, which are common in snRNP proteins. SIMILARITY: Belongs to the SMN family. SIMILARITY: Contains 1 Tudor domain. GENE SYNONYMS:SMNDC1 SMNR SPF30. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 238 AA; 26711 MW; 7F60852AD4D1F53A CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:16900,
urn:biopax:RelationshipXref:NCBI GENE_10285,
urn:biopax:RelationshipXref:REFSEQ_NP_005862,
urn:biopax:UnificationXref:UNIPROT_B2RA27,
urn:biopax:UnificationXref:UNIPROT_D3DRB1,
urn:biopax:UnificationXref:UNIPROT_O75940,
urn:biopax:UnificationXref:UNIPROT_Q5T3K6
|
| biopax3:displayName |
SPF30_HUMAN
|
| biopax3:name |
30 kDa splicing factor SMNrp,
SMN-related protein,
SMNDC1,
Survival motor neuron domain-containing protein 1
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
|
| biopax3:standardName |
Survival of motor neuron-related-splicing factor 30
|