Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. SUBUNIT: Interacts with dsRNA (By similarity). SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus (By similarity). TISSUE SPECIFICITY: Constitutively expressed in brain and testis. Also expressed in lung, kidney and spleen after whole body gamma irradiation. INDUCTION: By DNA damage in a p53-dependent manner, and by methamphetamine (METH) in a catecholaminergic cell line. SIMILARITY: Contains 3 matrin-type zinc fingers. GENE SYNONYMS:Zmat3 Pag608 Wig1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 290 AA; 32001 MW; 32E545A54E04581B CRC64;
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biopax3:xref | |
biopax3:displayName |
ZMAT3_MOUSE
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biopax3:name |
Wild-type p53-induced gene 1 protein,
Zinc finger protein WIG-1,
Zmat3,
p53-activated gene 608 protein
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biopax3:organism | |
biopax3:sequence |
MILLQQVWLPLPNRPSTSPPMSVAARSTRTLQLPPQKAFGQEASLPLAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARVSSVVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVATRRNMNPVQSNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ
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biopax3:standardName |
Zinc finger matrin-type protein 3
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