| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. SUBUNIT: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/PAM16 and TIMM14/DNAJC19 (By similarity). The complex interacts with the TIMM23 component of the TIM23 complex. SUBCELLULAR LOCATION: Mitochondrion inner membrane. SIMILARITY: Belongs to the Tim44 family. GENE SYNONYMS:TIMM44 MIMT44 TIM44. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 452 AA; 51356 MW; 15BECF875611BE96 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:17316,
urn:biopax:RelationshipXref:NCBI GENE_10469,
urn:biopax:RelationshipXref:REFSEQ_NP_006342,
urn:biopax:UnificationXref:UNIPROT_A8K0R9,
urn:biopax:UnificationXref:UNIPROT_D6W664,
urn:biopax:UnificationXref:UNIPROT_O43615,
urn:biopax:UnificationXref:UNIPROT_Q8N193
|
| biopax3:displayName |
TIM44_HUMAN
|
| biopax3:name |
TIMM44
|
| biopax3:organism | |
| biopax3:sequence |
MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISASSTEQIL
|
| biopax3:standardName |
Mitochondrial import inner membrane translocase subunit TIM44
|