| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). TISSUE SPECIFICITY: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. DOMAIN: The first RNA recognition motif binds more strongly to RNA compared to the second one (By similarity). SIMILARITY: Belongs to the Musashi family. SIMILARITY: Contains 2 RRM (RNA recognition motif) domains. GENE SYNONYMS:MSI1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 362 AA; 39125 MW; 26487B0A32CF1F40 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:7330,
urn:biopax:RelationshipXref:NCBI GENE_4440,
urn:biopax:RelationshipXref:REFSEQ_NP_002433,
urn:biopax:UnificationXref:UNIPROT_O43347,
urn:biopax:UnificationXref:UNIPROT_Q96PU0,
urn:biopax:UnificationXref:UNIPROT_Q96PU1,
urn:biopax:UnificationXref:UNIPROT_Q96PU2,
urn:biopax:UnificationXref:UNIPROT_Q96PU3
|
| biopax3:displayName |
MSI1H_HUMAN
|
| biopax3:name |
MSI1,
Musashi-1
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
|
| biopax3:standardName |
RNA-binding protein Musashi homolog 1
|