| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. SUBUNIT: Interacts with ER-alpha N-terminal activation domain. SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=10; Name=1; IsoId=O43251-1; Sequence=Displayed; Name=2; IsoId=O43251-2; Sequence=VSP_007180, VSP_030890; Name=3; IsoId=O43251-3; Sequence=VSP_007180, VSP_007181, VSP_007182; Note=No experimental confirmation available; Name=4; IsoId=O43251-4; Sequence=VSP_007180, VSP_007183; Note=No experimental confirmation available; Name=5; IsoId=O43251-5; Sequence=VSP_007180, VSP_007182; Note=No experimental confirmation available; Name=6; IsoId=O43251-6; Sequence=VSP_030889; Note=Ref.4 (BAB70875) sequence is in conflict in position: 8:H->Q; Name=7; IsoId=O43251-7; Sequence=VSP_007182, VSP_030891; Name=8; IsoId=O43251-8; Sequence=VSP_030889, VSP_030890; Name=9; IsoId=O43251-9; Sequence=VSP_007180, VSP_030890, VSP_007182, VSP_007183; Name=10; IsoId=O43251-10; Sequence=VSP_007180; SIMILARITY: Contains 1 RRM (RNA recognition motif) domain. GENE SYNONYMS:RBFOX2 FOX2 HRNBP2 RBM9 RTA. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 390 AA; 41374 MW; 40D6C8C40764B317 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:9906,
urn:biopax:RelationshipXref:NCBI GENE_23543,
urn:biopax:RelationshipXref:REFSEQ_NP_001026865,
urn:biopax:RelationshipXref:REFSEQ_NP_001076045,
urn:biopax:RelationshipXref:REFSEQ_NP_001076046,
urn:biopax:RelationshipXref:REFSEQ_NP_001076047,
urn:biopax:RelationshipXref:REFSEQ_NP_001076048,
urn:biopax:RelationshipXref:REFSEQ_NP_055124,
urn:biopax:UnificationXref:UNIPROT_A4F5G8,
urn:biopax:UnificationXref:UNIPROT_A8K5Z5,
urn:biopax:UnificationXref:UNIPROT_B0QYY8,
urn:biopax:UnificationXref:UNIPROT_B0QYY9,
urn:biopax:UnificationXref:UNIPROT_O43251,
urn:biopax:UnificationXref:UNIPROT_Q0PRL5,
urn:biopax:UnificationXref:UNIPROT_Q0VH35,
urn:biopax:UnificationXref:UNIPROT_Q5TF71,
urn:biopax:UnificationXref:UNIPROT_Q6IC09,
urn:biopax:UnificationXref:UNIPROT_Q8TD00,
urn:biopax:UnificationXref:UNIPROT_Q8WYB1,
urn:biopax:UnificationXref:UNIPROT_Q96DZ6,
urn:biopax:UnificationXref:UNIPROT_Q96NL7,
urn:biopax:UnificationXref:UNIPROT_Q9UGW4,
urn:biopax:UnificationXref:UNIPROT_Q9UH33
|
| biopax3:displayName |
RFOX2_HUMAN
|
| biopax3:name |
Fox-1 homolog B,
Hexaribonucleotide-binding protein 2,
RBFOX2,
RNA-binding motif protein 9,
RNA-binding protein 9,
Repressor of tamoxifen transcriptional activity
|
| biopax3:organism | |
| biopax3:sequence |
MQNEPLTPGYHGFPARDSQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY
|
| biopax3:standardName |
RNA binding protein fox-1 homolog 2
|