| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). FUNCTION: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity). FUNCTION: Leumorphin has a typical opiod activity and may have anti-apoptotic effect (By similarity). SUBCELLULAR LOCATION: Secreted. PTM: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. SIMILARITY: Belongs to the opioid neuropeptide precursor family. GENE SYNONYMS:Pdyn. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 248 AA; 28055 MW; EDD49766CCD5DA6E CRC64;
|
| biopax3:xref | |
| biopax3:displayName |
PDYN_MOUSE
|
| biopax3:name |
Alpha-neoendorphin,
Beta-neoendorphin,
Beta-neoendorphin-dynorphin,
Big Dyn,
Big dynorphin,
Dyn-A17,
Dyn-B,
Dynorphin A,
Dynorphin A(1-13),
Dynorphin A(1-17),
Dynorphin A(1-8),
Dynorphin B,
Dynorphin B(1-13),
Dynorphin B-29,
Leu-enkephalin,
Leumorphin,
Pdyn,
Preprodynorphin,
Rimorphin
|
| biopax3:organism | |
| biopax3:sequence |
MAWSRLMLAACLLVMPSNVMADCLSLCSLCAVRIQDGPRPINPLICSLECQDLVPPSEEWETCRGFSSFLTLTVSGLRGKDDLEDEVALEEGISAHAKLLEPVLKELEKSRLLTSVPEEKFRGLSSSFGNGKESELAGADRMNDEAAQGRTVHFNEEDLRKQAKRYGGFLRKYPKRSSEMARDEDGGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYSEDLDV
|
| biopax3:standardName |
Proenkephalin-B
|