| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: May be an organic anion pump relevant to cellular detoxification. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O15439-1; Sequence=Displayed; Name=2; IsoId=O15439-2; Sequence=VSP_035426; Name=3; IsoId=O15439-3; Sequence=VSP_043283, VSP_043284; Note=No experimental confirmation available; TISSUE SPECIFICITY: Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. SIMILARITY: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. SIMILARITY: Contains 2 ABC transmembrane type-1 domains. SIMILARITY: Contains 2 ABC transporter domains. GENE SYNONYMS:ABCC4 MRP4. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 1325 AA; 149527 MW; BF2D53136B78C0BA CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:55,
urn:biopax:RelationshipXref:NCBI GENE_10257,
urn:biopax:RelationshipXref:REFSEQ_NP_001098985,
urn:biopax:RelationshipXref:REFSEQ_NP_005836,
urn:biopax:UnificationXref:UNIPROT_A9Z1Z7,
urn:biopax:UnificationXref:UNIPROT_O15439,
urn:biopax:UnificationXref:UNIPROT_Q8IVZ4,
urn:biopax:UnificationXref:UNIPROT_Q8IZN6,
urn:biopax:UnificationXref:UNIPROT_Q8NEW8,
urn:biopax:UnificationXref:UNIPROT_Q9Y6J2
|
| biopax3:displayName |
MRP4_HUMAN
|
| biopax3:name |
ABCC4,
ATP-binding cassette sub-family C member 4,
MOAT-B,
MRP/cMOAT-related ABC transporter,
Multi-specific organic anion transporter B
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL
|
| biopax3:standardName |
Multidrug resistance-associated protein 4
|