| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity. CATALYTIC ACTIVITY: Transfers a beta-D-GlcNAc residue from UDP-D- GlcNAc to the fucose residue of a fucosylated protein acceptor. COFACTOR: Manganese (By similarity). SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00587-1; Sequence=Displayed; Name=2; IsoId=O00587-2; Sequence=VSP_042857; Note=No experimental confirmation available; SIMILARITY: Belongs to the glycosyltransferase 31 family. WEB RESOURCE: Name=GGDB; Note=GlycoGene database; URL="http://riodb.ibase.aist.go.jp/rcmg/ggdb/"; WEB RESOURCE: Name=Functional Glycomics Gateway - GTase; Note=Beta-1,3-N-acetylglucosaminyltransferase manic fringe; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_552"; GENE SYNONYMS:MFNG. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 321 AA; 36202 MW; 7CB847E7423DD0BC CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:7038,
urn:biopax:RelationshipXref:NCBI GENE_4242,
urn:biopax:RelationshipXref:REFSEQ_NP_001159815,
urn:biopax:RelationshipXref:REFSEQ_NP_002396,
urn:biopax:UnificationXref:UNIPROT_B4DLT6,
urn:biopax:UnificationXref:UNIPROT_O00587,
urn:biopax:UnificationXref:UNIPROT_O43730,
urn:biopax:UnificationXref:UNIPROT_Q504S9
|
| biopax3:displayName |
MFNG_HUMAN
|
| biopax3:name |
2.4.1.222,
MFNG,
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
| biopax3:organism | |
| biopax3:sequence |
MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR
|
| biopax3:standardName |
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
|