Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. SUBUNIT: Interacts with PICK1 (By similarity). SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=A; Synonyms=mGluR8a; IsoId=O00222-1; Sequence=Displayed; Name=B; Synonyms=mGluR8b; IsoId=O00222-2; Sequence=VSP_002032; Name=C; Synonyms=mGluR8c; IsoId=O00222-3; Sequence=VSP_002033, VSP_002034; SIMILARITY: Belongs to the G-protein coupled receptor 3 family. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/grm8/"; GENE SYNONYMS:GRM8 GPRC1H MGLUR8. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 908 AA; 101741 MW; 95C2D5883DAF6FDE CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:4600,
urn:biopax:RelationshipXref:NCBI GENE_2918,
urn:biopax:RelationshipXref:REFSEQ_NP_000836,
urn:biopax:RelationshipXref:REFSEQ_NP_001120795,
urn:biopax:UnificationXref:UNIPROT_A4D0Y3,
urn:biopax:UnificationXref:UNIPROT_B0FZ74,
urn:biopax:UnificationXref:UNIPROT_B0M0L0,
urn:biopax:UnificationXref:UNIPROT_O00222,
urn:biopax:UnificationXref:UNIPROT_O15493,
urn:biopax:UnificationXref:UNIPROT_O95945,
urn:biopax:UnificationXref:UNIPROT_O95946,
urn:biopax:UnificationXref:UNIPROT_Q3MIV9,
urn:biopax:UnificationXref:UNIPROT_Q52M02,
urn:biopax:UnificationXref:UNIPROT_Q6J165
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biopax3:displayName |
GRM8_HUMAN
|
biopax3:name |
GRM8,
mGluR8
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biopax3:organism | |
biopax3:sequence |
MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI
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biopax3:standardName |
Metabotropic glutamate receptor 8
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