Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. SUBUNIT: Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A. SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Mainly localized to the plasma membrane. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=SNAP-23a; IsoId=O00161-1; Sequence=Displayed; Name=SNAP-23b; IsoId=O00161-2; Sequence=VSP_006187, VSP_006188; TISSUE SPECIFICITY: Ubiquitous. Highest levels where found in placenta. SIMILARITY: Belongs to the SNAP-25 family. SIMILARITY: Contains 2 t-SNARE coiled-coil homology domains. GENE SYNONYMS:SNAP23. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 211 AA; 23354 MW; AC378E9786C3A239 CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11131,
urn:biopax:RelationshipXref:NCBI GENE_8773,
urn:biopax:RelationshipXref:REFSEQ_NP_003816,
urn:biopax:RelationshipXref:REFSEQ_NP_570710,
urn:biopax:UnificationXref:UNIPROT_O00161,
urn:biopax:UnificationXref:UNIPROT_O00162,
urn:biopax:UnificationXref:UNIPROT_Q13602,
urn:biopax:UnificationXref:UNIPROT_Q6IAE3
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biopax3:displayName |
SNP23_HUMAN
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biopax3:name |
SNAP-23,
SNAP23,
Vesicle-membrane fusion protein SNAP-23
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biopax3:entityFeature | |
biopax3:organism | |
biopax3:sequence |
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPGPVTNGQLQQPTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS
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biopax3:standardName |
Synaptosomal-associated protein 23
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