| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:chemicalFormula |
C62H111N11O12
|
| biopax3:comment |
A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.
|
| biopax3:xref |
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:25212,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:35705,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:35718,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:35842,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:49167,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:50177,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:50903,
urn:biopax:RelationshipXref:HAS_ROLE_CHEBI:62670,
urn:biopax:UnificationXref:CHEBI_CHEBI:4031,
urn:biopax:UnificationXref:CHEBI_CHEBI:63586,
urn:biopax:UnificationXref:INCHI_PMATZTZNYRCHOR-VJRYSDSKSA-N,
urn:biopax:UnificationXref:PUBCHEM_8147029
|
| biopax3:displayName |
cyclosporin A
|
| biopax3:name |
(R-[R*,R*-(E)])-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl),
1,11-cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(E)-(2S,3R,4R)-2-amino-3-hydroxy-N,4-dimethyloct-6-enoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine],
30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone,
30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone,
Antibiotic S 7481F1,
Ciclosporin,
Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl)-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl),
Cyclosporin A,
Cyclosporine
|
| biopax3:molecularWeight |
1202.61
|
| biopax3:standardName |
cyclosporin A
|
| biopax3:structure |