| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Inosine-5'-monophosphate dehydrogenase is the rate-limiting enzyme of <i>de novo</i> GTP biosynthesis. Two isoforms that are 84% identical at the amino acid level.exist in humans - |FRAME: HS02896| and |FRAME: HS11242| |CITS: [1969416]|. The |FRAME: HS11242| gene has been assigned to chromosome 3p21.2-->p24.2 |CITS: [8098009][9858805]|.The gene was cloned and shown to contain 14 exons and to be approximately 5.8 kilobases in length |CITS: [7896827][ 7999076]|. Expression of the gene is increased more than 10-fold in activated peripheral blood T lymphocytes and is required for T cell activation |CITS: [9278455]|. The human enzyme has been expressed in and purified from Escherichia coli |CITS: [7763314]|.
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| biopax3:component | |
| biopax3:componentStoichiome... | |
| biopax3:dataSource | |
| biopax3:displayName |
IMPD 2
|
| biopax3:name |
IMP dehydrogenase 2
|
| biopax3:standardName |
inosine-5'-monophosphate dehydrogenase 2
|