Source:HTTP://PATHWAYCOMMONS.ORG/PSI2BP#_9158335020446588302
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biopax3:comment |
2006 publication year MI:0886,
6 last-imex-assigned,
Apoptosis - Interactions involving proteins with a function related to apoptosis dataset MI:0875,
Cell (0092-8674) journal MI:0885,
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.,
In order to capture transient or weak interactions that occur as CFTR transits through different subcellular compartments, immunoprecipitations were carried out in the presence of the cleavable chemical cross-linker dithiobissuccinimidylpropionate (DSP) that was added to intact cells prior to cell lysis. exp-modification MI:0627,
Only protein-protein interactions full coverage MI:0957,
Synapse - Interactions of proteins with an established role in the presynapse. dataset MI:0875,
The gene names and the ref_seq identifiers were used to extract UniProtKB accession numbers. The UniProt-SwissProt identifiers and then the longest sequence were preferentially chosen. The Protein sequence allignment against human sequences was performed where proteins from alternative sources were identified. data-processing MI:0633,
This interaction was also studied in BHK cell line, however only 3% of the interacting proteins could be mapped to UniProtKB entries. comment MI:0612,
Wang X., Venable J., LaPointe P., Hutt DM., Koulov AV., Coppinger J., Gurkan C., Kellner W., Matteson J., Plutner H., Riordan JR., Kelly JW., Yates JR., Balch WE. author-list MI:0636,
imex curation MI:0959,
imex curation curation depth MI:0955,
webalch@scripps.edu,jyates@scripps.edu contact-email MI:0634
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