| http://www.reactome.org/bio... | rdf:type | biopax3:BiochemicalReaction | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Reviewed: Simon, V, 2007-01-30 23:07:12 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Reviewed: Mulder, L, 2007-01-30 22:57:00 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Edited: Matthews, L, 2007-01-30 11:27:41 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Authored: Matthews, L, 2006-06-07 20:09:24 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | During reverse transcription, APOBEC3G-mediated minus-strand deamination occurs within a CC dinucleotide context over the entire length of the HIV-1 genome (Yu et al., 2004). <br>The polypurine tract is essential for plus strand synthesis and is located at the 3� end of the retroviral genome. HIV-1 encodes an additional central polypurine tract located in the middle of the genome which also serves as primer for plus strand synthesis.<br>Deamination of the minus strand continues throughout its synthesis with the frequency of deamination events increasing from the 5� to 3� regions. A 400bp region downstream of the central polypurine tract seems to be protected from deamination (Wurtzer et al., 2006) | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | http://identifiers.org/pubm... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | http://identifiers.org/pubm... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | http://identifiers.org/pubm... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | urn:biopax:Provenance:react... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:displayName | Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:eCNumber | 3.5.4.13 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:left | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:left | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:right | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:right | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:stepProcess | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:controlled | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:pathwayComponent | http://www.reactome.org/bio... | lld:biopax3 |
