| http://purl.uniprot.org/enz... | rdf:type | uniprot:Enzyme | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | This amidase catalyzes the last step in the conversion of an L-histidine residue in the translation elongation factor eEF-2 to diphthamide. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | This factor is found in all archaebacteria and eukaryotes, but not in eubacteria, and is the target of bacterial toxins such as the diphtheria toxin and the Pseudomonas exotoxin A (see EC 2.4.2.36). | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | The substrate of the enzyme, diphthine, is produced by EC 2.1.1.98. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | The nature of the ammonia donor is not known. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:subClassOf | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:broaderTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Diphthine--ammonia ligase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Diphthamide synthase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Diphthamide synthetase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:replaces | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:activity | ATP + diphthine + NH(3) = ADP + phosphate + diphthamide. | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:narrowerTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:replacedBy | http://purl.uniprot.org/enz... | lld:uniprot |
