Biochem. Biophys. Res. Commun.

Nucleotide sequences of two mouse cDNAs encoding new sulfotransferase enzymes were determined. Analysis of the deduced amino acid sequences revealed that one represents a novel member of the phenol sulfotransferase family and the other is highly homologous to human SULT2B1 hydroxysteroid sulfotransferases. The recombinant enzymes, transiently expressed in COS-7 cells, were characterized with respect to their substrate specificity using a variety of substrates for different types of sulfotransferases. The tissue-specific expression of these two new mouse sulfotransferases was examined by Northern blot analysis.

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http://purl.uniprot.org/cit...rdfs:commentNucleotide sequences of two mouse cDNAs encoding new sulfotransferase enzymes were determined. Analysis of the deduced amino acid sequences revealed that one represents a novel member of the phenol sulfotransferase family and the other is highly homologous to human SULT2B1 hydroxysteroid sulfotransferases. The recombinant enzymes, transiently expressed in COS-7 cells, were characterized with respect to their substrate specificity using a variety of substrates for different types of sulfotransferases. The tissue-specific expression of these two new mouse sulfotransferases was examined by Northern blot analysis.lld:uniprot
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http://purl.uniprot.org/cit...uniprot:authorYanagisawa K.lld:uniprot
http://purl.uniprot.org/cit...uniprot:authorNakayama T.lld:uniprot
http://purl.uniprot.org/cit...uniprot:authorTakami Y.lld:uniprot
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http://purl.uniprot.org/cit...uniprot:titleMolecular cloning, expression, and functional characterization of novel mouse sulfotransferases.lld:uniprot
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