Rapid development. Cells are 4-fold more resistant to the antitumor agent cisplatin than are wild-type cells. Additionally it produces fruiting bodies with spore masses that cannot rise up the stalk during development. Mutant cells grow exponentially at the same rate as wild-type. Disruption of regA in a tagB null or in a tagC null background resulted in higher levels of sporulation. Disruption of regA in a dhka null background corrects the defect in stalk formation and suppresses the block to sporulation.
| Subject | Predicate | Object | Context |
|---|---|---|---|
| http://purl.uniprot.org/SHA... | rdf:type | uniprot:Disruption_Phenotyp... | lld:uniprot |
| http://purl.uniprot.org/SHA... | rdfs:comment | Rapid development. Cells are 4-fold more resistant to the antitumor agent cisplatin than are wild-type cells. Additionally it produces fruiting bodies with spore masses that cannot rise up the stalk during development. Mutant cells grow exponentially at the same rate as wild-type. Disruption of regA in a tagB null or in a tagC null background resulted in higher levels of sporulation. Disruption of regA in a dhka null background corrects the defect in stalk formation and suppresses the block to sporulation. | lld:uniprot |
| uniprot-protein:Q23917 | uniprot:annotation | http://purl.uniprot.org/SHA... | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:subject | http://purl.uniprot.org/SHA... | lld:uniprot |