Linked Life Data

5594-155871

Source:http://linkedlifedata.com/resource/entrezgene/interaction/5594-155871

Statements in which the resource exists.
SubjectPredicateObjectContext
http://linkedlifedata.com/r...rdf:typeentrezgene:Interactionlld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:22362758lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10799874lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:20019835lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21483469lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10780709lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9223324lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:20457808lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:16436505lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:20839920lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18092356lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:12491158lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:20336759lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:12167619lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18760861lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18538010lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9558095lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:16920714lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18692180lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18160848lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:19287189lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:20849923lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21172429lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9621077lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:22553998lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21368226lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:11260070lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21745501lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18854243lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:19622906lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:18569454lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:16539678lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:22937208lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10982368lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:11044099lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:17868650lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10509564lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:11409852lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:16395283lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:12482669lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:11579140lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:16741963lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:22487967lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10074203lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:9325171lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21840940lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21821233lld:entrezgene
http://linkedlifedata.com/r...entrezgene:interactantentrez-gene:155871lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat in combination with KSHV kaposin A activates the MEK/ERK, STAT3, and PI3K/Akt signals in NIH3T3 cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat alters the properties of human neural precursor cells via attenuation of the cell cycle regulatory unit cyclin D1 and the mitogen-activated protein kinase (MAPK) pathway, particularly extracellular signal-related kinase 1/2 (ERK1/2)lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextTat-triggered PKCdelta and PKCtheta activation results in the downstream signaling through the apoptosis pathways mediated by both ERK1/2 and caspase-3lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextTat activates at least three signaling pathways concurrently, including NF-kappaB, PKC, ERK1/2 and p38 MAP kinases and IKKalpha pathways, to promote production of IL-10lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextCell-permeable SOD inhibits the activation of MAP kinases including ERK, JNK and p38 and the upregulation of ICAM-1 and VCAM-1 by HIV-1 Tatlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat-induced MAPK (ERK, JNK, and p38) activation is required for MMP-9 expression in human astrocyteslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat-induced glutamate release is mediated through p38 and p42/44 MAPK and through NADPH oxidase and the x(c)(-) cystine-glutamate antiporter (xCT)lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextKnocking down Nox2 by siRNA decreases HIV-1 Tat-induced NF-KappaB activation as well as activation of MAP kinases including ERK, JNK, and p38lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat-linked intracellular third loop of the endothelin-1 type B receptor markedly enhances the endothelin-1 activation of ERK in the bone morphogenetic protein-2 receptor human pulmonary artery smooth muscle cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1-Tat-mediated upregulation of platelet-derived growth factor (PDGF) B chain in astrocytes is regulated by activation of ERK1/2 and JNK MAPK signaling pathways and the downstream transcription factor early growth response 1 (Egr1)lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextThe binding between HIV-1 Tat and Grb2 is mediated by the proline-rich sequence (residues 1-18) of Tat and the SH3 domain (residues 160-212) of Grb2, which impairs activation of the Raf/MAPK pathway and increases the PKA/Raf inhibitory pathwaylld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat induces ERK phosphorylation by the activation of the small GTPase Ras, but not the small GTPase Rac, in human endothelial cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextTat and IFN-gamma synergistically induce the expression of CXCL10, which is inhibited by MEK1/2 inhibitor and the p38 mitogen-activated protein kinase (MAPK) inhibitorlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat- and oxovanadate-treated microglial cells synergistically induce release of TNF-a and IL-1 proteins, which involves CD45 and ERK1/2 signaling pathwayslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextThe interaction of HIV-1 Tat with KDR/VEGFR2 is implicated in the activation of ERK1 and ERK2 signaling pathwayslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextAdhesion of endothelial cells to HIV-1 Tat triggers a signal transduction pathway, which leads to phosphorylation of VEGFR2 and pp60src and activation of ERK1/2lld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextFormation of the Nef-associated kinase complex (NAKC) is sufficient to activate LCK and ERK1/2 and causes a strong Tat-dependent increase of HIV-1 transcription in T cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextExpression of HIV-1 Tat in human SK-N-MC cells inhibits the NGF-signaling pathway leading to suppression of MAPK and reduction of Puralpha binding to the Egr-1 promoterlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextPhospholipase C/protein kinase C signaling pathway-dependent phosphorylation of p44/42 and JNK MAP kinases participates partially in IL-1beta induction by TATlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat activates ERK1 and ERK2 through the activation of MEK1 and MEK2, leading to induction of IL-8, IL-10, IP-10, iNOS, superoxide and TNF-alpha, as well as suppression of p35 activator of cdk5, activation of CREB and increased albumin permeabilitylld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat is phosphorylated by MAPK in vitrolld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextTreatment with HIV-1 Tat induces phosphorylation of ERK1/2 and JNK in brain micro vascular endothelial cells (BMEC) and astrocytes, which mediates Tat-induced multidrug resistance-associated protein 1 (MRP1) expressionlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextSulfated polymannuroguluronate (SPMG) blocks the Tat-induced extracellular-signal regulated kinase 1/2- and c-jun amino-terminal kinase-mediated signalling pathwayslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat inhibits the LPS-activation of ERK1/2 but not the p38 mitogen-activated protein kinases in primary blood monocytes/macrophageslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat and morphine-induced apoptosis in human neuroblastoma cells involves ERK1/2 and JNK activationlld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextHIV-1 Tat-induced upregulation of B7-H1 protein expression requires activation of the ERK/MAPK signaling pathway in human endothelial cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:geneRifTextThe NADPH oxidase inhibitors DPI and apocynin abrogate HIV-1 Tat-stimulated ERK1/2 activation in human microglia-like cellslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseinhibitslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseinteracts withlld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphrasecooperates withlld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseinduces phosphorylation oflld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphrasemodulateslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseactivateslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseinactivateslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseenhanceslld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphrasephosphorylated bylld:entrezgene
http://linkedlifedata.com/r...entrezgene:keyphraseactivated bylld:entrezgene
entrez-gene:5594entrezgene:interactionhttp://linkedlifedata.com/r...lld:entrezgene