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MEDLINEPLUS: <p>Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Skin cells give your skin color by making a substance called melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin. Others affect your entire body. </p><p>If your body makes too much melanin, your skin gets darker. Pregnancy, Addison's disease and sun exposure all can make your skin darker. If your body makes too little melanin, your skin gets lighter. <a href='http://www.nlm.nih.gov/medlineplus/vitiligo.html'>Vitiligo</a> is a condition that causes patches of light skin. Albinism is a genetic condition affecting all of a person's skin. Infections, blisters and burns can cause lighter skin. </p>,NCI: A disorder of the skin characterized by loss or reduction of the skin color. It is caused by loss of melanocytes or abnormalities in melanin production.
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