Source:http://linkedlifedata.com/resource/umls/id/C1335671
NCI: Receptor Genes encode cell surface or cytoplasmic receptor proteins that each bind to specific signaling factors (such as a hormone, antigen, or neurotransmitter) causing a conformational and functional change in the ligand-bound receptor, altering its interaction with target molecules and leading to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.