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skos:definition |
CSP: various processes by which antibodies may regulate immune responses; at a simple level, secreted antibody neutralizes the antigen with which it reacts thus preventing further antigenic stimulation of the antibody producing clone; at a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases and perhaps further anti-idiotype antibodies against them; this is the major concept of the immunological network theory.,NCI: Change in the body's immune system, caused by agents that activate or suppress its function.,NCI: Physiologic control of immune function. Includes all levels of regulation from gene expression mechanisms, through cell-cell interactions, to organism-wide responses.
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