Source:http://linkedlifedata.com/resource/umls/id/C0677948
NCI: Stage II colorectal cancer is divided into stage IIA, stage IIB, and stage IIC. In stage IIA, cancer has spread through the muscle layer of the colon and/or rectal wall to the serosa (outermost layer) of the colon and/or rectal wall. In stage IIB, cancer has spread through the serosa of the colon and/or rectal wall but has not spread to nearby organs. In stage IIC, cancer has spread through the serosa of the colon and/or rectal wall to nearby organs.,NCI: Stage Group II is subdivided into IIA and IIB on the basis of whether the primary tumor is T3 or T4, respectively. T3: Tumor invades through the muscularis propria into the subserosa, or into non-peritonealized pericolic or perirectal tissues. T4: Tumor directly invades other organs or structures, and/or perforates visceral peritoneum. (AJCC 6th ed.) - 2003