skos:definition |
MSH: Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.,NCI: A chronic inflammatory disorder characterized by hyperostosis, osteitis, synovitis and palmoplantar pustulosis. The most common site of involvement is the anterior chest wall.
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