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skos:definition |
NCI: Metallothionein 3, encoded by the human MT3 gene, belongs to family 1 of the metallothionein superfamily. Metallothionein 3 contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. It binds heavy metals. Metallothionein 3 inhibits survival and neurite formation of cortical neurons in vitro. It is abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the alzheimer's disease (AD) brain. (from Swiss-Prot)
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