Sarcoma, Clear Cell


MSH: A sarcoma of young, often female, adults of the lower extremities and acral regions, intimately bound to tendons as circumscribed but unencapsulated melanin-bearing tumors of neuroectodermal origin. An ultrastructural finding simulates flattened and curved barrel staves, corresponding to the internal structures of premelanosomes. There is a 45-60% mortality in clear cell sarcoma. (Segen, Dictionary of Modern Medicine, 1992),NCI: A soft tissue tumor of young adults with melanocytic differentiation, typically involving tendons and aponeuroses. There is a recurrent cytogenetic aberration: t(12;22)(q13;q12).,NCI: A rare malignant neoplasm with melanocytic differentiation characterized by the presence of polygonal or spindle shaped clear cells. This sarcoma usually affects the tendons and aponeuroses and is associated with a poor prognosis due to recurrences and metastases.,NCI: A soft tissue tumor that begins in a tendon (tough, fibrous, cord-like tissue that connects muscle to bone or to another structure).

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