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skos:definition |
MSH: Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.,NCI: Processes that result in the removal of B and T lymphocytes which have specificity for self antigens.
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