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| skos:definition |
PDQ: A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39577&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39577&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1304" NCI Thesaurus),NCI: A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from
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| umls:relation |
http://linkedlifedata.com/resource/umls/relation/R128529261,
http://linkedlifedata.com/resource/umls/relation/R128529262,
http://linkedlifedata.com/resource/umls/relation/R129080020,
http://linkedlifedata.com/resource/umls/relation/R60461547,
http://linkedlifedata.com/resource/umls/relation/R60459844,
http://linkedlifedata.com/resource/umls/relation/R22540272,
http://linkedlifedata.com/resource/umls/relation/R124677386,
http://linkedlifedata.com/resource/umls/relation/R124677387,
http://linkedlifedata.com/resource/umls/relation/R54314677,
http://linkedlifedata.com/resource/umls/relation/R54184693,
http://linkedlifedata.com/resource/umls/relation/R54422599,
http://linkedlifedata.com/resource/umls/relation/R54422596,
http://linkedlifedata.com/resource/umls/relation/R54422600,
http://linkedlifedata.com/resource/umls/relation/R54396559,
http://linkedlifedata.com/resource/umls/relation/R69803442,
http://linkedlifedata.com/resource/umls/relation/R03105205
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