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skos:definition |
MSH: A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.,NCI: Macrophage colony-stimulating factor 1 receptor (972 aa, 108 kD) is a cell division process protein that is encoded by the human CSF1R gene and has roles in macrophage differentiation and regulation of cell proliferation.
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