| umls-concept:C0079323 | skos:definition | MSH: Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).,CSP: diverse family of proteins found in extracellular matrix.,NCI: Encoded by Extracellular Matrix Protein Genes, Extracellular Matrix Proteins are mostly fibrous proteins (e.g., Collagen, Elastin, Fibronectins, and Laminin) typically located in the Extracellular Matrix and commonly involved in cell attachment, cell movement, cell growth, morphogenesis, organogenesis, and tissue repair, architecture, and org | lld:umls |
