Source:http://linkedlifedata.com/resource/umls/id/C0059735
MSH: A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.,NCI: A cytochrome P-450 enzyme capable of activating procarcinogenic polycyclic hydrocarbons and halogenated aromatic hydrocarbons into mutagenic compounds. Ethoxyresorufin acts as a substrate for CYP1A1 and measurement of ethoxyresorufin O-deethylase provides a more direct method of detection for this enzyme. EC 1.-.