MSH: A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS.,CSP: condition of morphologic change in which there is accumulation of lipids in the large foam cells of tissues; the cutaneous manifestation of lipidosis in which plasma fatty acids and lipoproteins are quantitatively changed.

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