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MSH: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.,CSP: heterogeneous group of hereditary hemolytic anemias which have in common a decreased rate of synthesis of one or more hemoglobin polypeptide chains.,MEDLINEPLUS: <p>If you have thalassemia, your body has problems making hemoglobin, the protein in red blood cells that carries oxygen through your body. When your blood does not carry enough oxygen to the rest of your body, you have <a href='http://www.nlm.nih.gov/medlineplus/anemia.html'>anemia</a>.</p><p>Thalassemia, a genetic disease, can be mild or severe. Some carriers of the gene have no symptoms. The most common severe form in the United States is a type called Cooley's anemia. It mainly affects people of Mediterranean or Asian ancestry. It usually appears during the first two years of lif
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