|
rdf:type |
|
|
calbc:hasCorrelation |
|
|
skos:exactMatch |
|
|
skos:definition |
NCI: The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally high levels on the surface of many types of cancer cells, so these cells may divide excessively in the presence of epidermal growth factor.,MSH: A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.,NCI: Epidermal growth factor receptor (1210 aa, ~134 kDa) is encoded by the human EGFR gene. This protein plays a role in cell-cell adhesion, cell migration, cell proliferation and signal transduction.
|
|
skos:inScheme |
|
|
skos:narrower |
umls-concept:C0082446,
umls-concept:C0214098,
umls-concept:C0378579,
umls-concept:C0527704,
umls-concept:C0639555,
umls-concept:C0915629,
umls-concept:C1121896,
umls-concept:C1257103,
umls-concept:C1434453,
umls-concept:C1435555,
umls-concept:C1568757,
umls-concept:C1678787,
umls-concept:C1739039,
umls-concept:C2716606
|
|
skos-xl:prefLabel |
|
|
skos-xl:altLabel |
umls-label:A0053043,
umls-label:A0109934,
umls-label:A0109935,
umls-label:A0130724,
umls-label:A0360670,
umls-label:A0360673,
umls-label:A0363251,
umls-label:A0363252,
umls-label:A10770552,
umls-label:A10773858,
umls-label:A10784554,
umls-label:A10785106,
umls-label:A11810102,
umls-label:A1306145,
umls-label:A1306146,
umls-label:A1625254,
umls-label:A1625255,
umls-label:A1625256,
umls-label:A1633166,
umls-label:A1633167,
umls-label:A1633214,
umls-label:A1633215,
umls-label:A1644945,
umls-label:A1645457,
umls-label:A1645458,
umls-label:A1655578,
umls-label:A17879721,
umls-label:A17879723,
umls-label:A17903815,
umls-label:A17903817,
umls-label:A17903818,
umls-label:A17928103,
umls-label:A17928104,
umls-label:A17928105,
umls-label:A17951903,
umls-label:A17951904,
umls-label:A17976201,
umls-label:A17999893,
umls-label:A18023623,
umls-label:A18047849,
umls-label:A18047850,
umls-label:A18047851,
umls-label:A18047852,
umls-label:A18321854,
umls-label:A18593688,
umls-label:A18593689,
umls-label:A18593690,
umls-label:A18593691,
umls-label:A18668084,
umls-label:A1930822,
umls-label:A1957388,
umls-label:A20235051,
umls-label:A20253405,
umls-label:A20256466,
umls-label:A2045966,
umls-label:A2045975,
umls-label:A4356746,
umls-label:A4358474,
umls-label:A7570221,
umls-label:A7574348,
umls-label:A7575899,
umls-label:A7575976,
umls-label:A7586372,
umls-label:A7586467,
umls-label:A7586478,
umls-label:A7587889
|
|
umls:relation |
|
