Philadelphia Chromosome

Source:http://linkedlifedata.com/resource/umls/id/C0031526

MSH: An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).,NCI: An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often found in chronic myelogenous leukemia.,NCI: A translocation between chromosomes 9 and 22. It is the hallmark for chronic myelogenous leukemia (CML).

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