omeprazole

calbc-group:ANAT, calbc-group:CHEM, calbc-group:CONC, calbc-group:DISO, calbc-group:PHEN, calbc-group:PHYS, calbc-group:PROC

MSH: A highly effective inhibitor of gastric acid secretion used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-EXCHANGING ATPASE) in the proton pump of GASTRIC PARIETAL CELLS.,CSP: substituted benzimidazole used as a gastric acid secretion inhibitor.,NCI: A drug that inhibits gastric acid secretion.,PDQ: A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic properties and does not antagonize histamine H2 receptors. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42309&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLin

umls-concept:C0003216, umls-concept:C0005065, umls-concept:C0014432, umls-concept:C0596593, umls-concept:C0682875

umls-label:A0094574

http://linkedlifedata.com/resource/umls/relation/R49863021, http://linkedlifedata.com/resource/umls/relation/R49863020, http://linkedlifedata.com/resource/umls/relation/R104210782, http://linkedlifedata.com/resource/umls/relation/R133618055, http://linkedlifedata.com/resource/umls/relation/R114282977, http://linkedlifedata.com/resource/umls/relation/R55154596, http://linkedlifedata.com/resource/umls/relation/R112186351, http://linkedlifedata.com/resource/umls/relation/R32105006, http://linkedlifedata.com/resource/umls/relation/R32105007, http://linkedlifedata.com/resource/umls/relation/R32105008, http://linkedlifedata.com/resource/umls/relation/R32105009, http://linkedlifedata.com/resource/umls/relation/R120389971, http://linkedlifedata.com/resource/umls/relation/R120389972, http://linkedlifedata.com/resource/umls/relation/R120389973, http://linkedlifedata.com/resource/umls/relation/R120389975, http://linkedlifedata.com/resource/umls/relation/R120389976, http://linkedlifedata.com/resource/umls/relation/R120389977, http://linkedlifedata.com/resource/umls/relation/R120389978, http://linkedlifedata.com/resource/umls/relation/R120389979, http://linkedlifedata.com/resource/umls/relation/R120389980, http://linkedlifedata.com/resource/umls/relation/R120389981, http://linkedlifedata.com/resource/umls/relation/R120389982, http://linkedlifedata.com/resource/umls/relation/R120389984, http://linkedlifedata.com/resource/umls/relation/R120389985, http://linkedlifedata.com/resource/umls/relation/R120389986, http://linkedlifedata.com/resource/umls/relation/R120389988, http://linkedlifedata.com/resource/umls/relation/R120389989, http://linkedlifedata.com/resource/umls/relation/R120389990, http://linkedlifedata.com/resource/umls/relation/R120389991, http://linkedlifedata.com/resource/umls/relation/R120389992, http://linkedlifedata.com/resource/umls/relation/R120389993, http://linkedlifedata.com/resource/umls/relation/R120389994, http://linkedlifedata.com/resource/umls/relation/R120389995, http://linkedlifedata.com/resource/umls/relation/R120389996, http://linkedlifedata.com/resource/umls/relation/R120389997, http://linkedlifedata.com/resource/umls/relation/R120389983, http://linkedlifedata.com/resource/umls/relation/R120389974, http://linkedlifedata.com/resource/umls/relation/R120389987, http://linkedlifedata.com/resource/umls/relation/R71366847, http://linkedlifedata.com/resource/umls/relation/R28123599, http://linkedlifedata.com/resource/umls/relation/R28123600, http://linkedlifedata.com/resource/umls/relation/R128883529, http://linkedlifedata.com/resource/umls/relation/R128883530, http://linkedlifedata.com/resource/umls/relation/R128883528, http://linkedlifedata.com/resource/umls/relation/R128883531, http://linkedlifedata.com/resource/umls/relation/R128883534, http://linkedlifedata.com/resource/umls/relation/R128883533, http://linkedlifedata.com/resource/umls/relation/R128883535, http://linkedlifedata.com/resource/umls/relation/R128883532, http://linkedlifedata.com/resource/umls/relation/R128883537, http://linkedlifedata.com/resource/umls/relation/R128883536, http://linkedlifedata.com/resource/umls/relation/R112189660, http://linkedlifedata.com/resource/umls/relation/R05220244, http://linkedlifedata.com/resource/umls/relation/R00694160, http://linkedlifedata.com/resource/umls/relation/R00694161, http://linkedlifedata.com/resource/umls/relation/R00694159, http://linkedlifedata.com/resource/umls/relation/R05246708, http://linkedlifedata.com/resource/umls/relation/R05246716, http://linkedlifedata.com/resource/umls/relation/R05246709, http://linkedlifedata.com/resource/umls/relation/R05246710, http://linkedlifedata.com/resource/umls/relation/R05246711, http://linkedlifedata.com/resource/umls/relation/R05246720, http://linkedlifedata.com/resource/umls/relation/R05246717, http://linkedlifedata.com/resource/umls/relation/R05246712, http://linkedlifedata.com/resource/umls/relation/R05246713, http://linkedlifedata.com/resource/umls/relation/R05246718, http://linkedlifedata.com/resource/umls/relation/R05246714, http://linkedlifedata.com/resource/umls/relation/R05246715, http://linkedlifedata.com/resource/umls/relation/R05246721, http://linkedlifedata.com/resource/umls/relation/R05246719, http://linkedlifedata.com/resource/umls/relation/R05246706, http://linkedlifedata.com/resource/umls/relation/R05246707, http://linkedlifedata.com/resource/umls/relation/R05675629, http://linkedlifedata.com/resource/umls/relation/R05675630, http://linkedlifedata.com/resource/umls/relation/R00896607, http://linkedlifedata.com/resource/umls/relation/R00896608, http://linkedlifedata.com/resource/umls/relation/R43989141, http://linkedlifedata.com/resource/umls/relation/R43989140, http://linkedlifedata.com/resource/umls/relation/R05741629, http://linkedlifedata.com/resource/umls/relation/R05741630, http://linkedlifedata.com/resource/umls/relation/R05741628, http://linkedlifedata.com/resource/umls/relation/R05741631, http://linkedlifedata.com/resource/umls/relation/R05741632, http://linkedlifedata.com/resource/umls/relation/R05741633, http://linkedlifedata.com/resource/umls/relation/R05741634, http://linkedlifedata.com/resource/umls/relation/R133940827, http://linkedlifedata.com/resource/umls/relation/R49873026, http://linkedlifedata.com/resource/umls/relation/R49873025, http://linkedlifedata.com/resource/umls/relation/R49873029, http://linkedlifedata.com/resource/umls/relation/R133618406, http://linkedlifedata.com/resource/umls/relation/R49873028, http://linkedlifedata.com/resource/umls/relation/R49873030, http://linkedlifedata.com/resource/umls/relation/R50924729, http://linkedlifedata.com/resource/umls/relation/R112406826, http://linkedlifedata.com/resource/umls/relation/R112406825, http://linkedlifedata.com/resource/umls/relation/R114283108, http://linkedlifedata.com/resource/umls/relation/R132425219, http://linkedlifedata.com/resource/umls/relation/R55157208, http://linkedlifedata.com/resource/umls/relation/R49873032, http://linkedlifedata.com/resource/umls/relation/R49873040, http://linkedlifedata.com/resource/umls/relation/R49873031, http://linkedlifedata.com/resource/umls/relation/R49873039, http://linkedlifedata.com/resource/umls/relation/R104211072, http://linkedlifedata.com/resource/umls/relation/R49873043, http://linkedlifedata.com/resource/umls/relation/R129360145, http://linkedlifedata.com/resource/umls/relation/R129360146, http://linkedlifedata.com/resource/umls/relation/R129360147, http://linkedlifedata.com/resource/umls/relation/R133618407, http://linkedlifedata.com/resource/umls/relation/R133618408, http://linkedlifedata.com/resource/umls/relation/R50925037, http://linkedlifedata.com/resource/umls/relation/R49873042, http://linkedlifedata.com/resource/umls/relation/R49873044, http://linkedlifedata.com/resource/umls/relation/R133618409, http://linkedlifedata.com/resource/umls/relation/R50925036, http://linkedlifedata.com/resource/umls/relation/R119241421, http://linkedlifedata.com/resource/umls/relation/R50925038, http://linkedlifedata.com/resource/umls/relation/R119241420, http://linkedlifedata.com/resource/umls/relation/R50925032, http://linkedlifedata.com/resource/umls/relation/R121408572, http://linkedlifedata.com/resource/umls/relation/R50925034, http://linkedlifedata.com/resource/umls/relation/R50925033, http://linkedlifedata.com/resource/umls/relation/R50925035, http://linkedlifedata.com/resource/umls/relation/R50925039, http://linkedlifedata.com/resource/umls/relation/R112406830, http://linkedlifedata.com/resource/umls/relation/R129360144, http://linkedlifedata.com/resource/umls/relation/R112406828, http://linkedlifedata.com/resource/umls/relation/R129360148, http://linkedlifedata.com/resource/umls/relation/R114283109, http://linkedlifedata.com/resource/umls/relation/R114283110, http://linkedlifedata.com/resource/umls/relation/R132425220, http://linkedlifedata.com/resource/umls/relation/R132425221, http://linkedlifedata.com/resource/umls/relation/R133940982, http://linkedlifedata.com/resource/umls/relation/R133940981, http://linkedlifedata.com/resource/umls/relation/R55157209, http://linkedlifedata.com/resource/umls/relation/R55131191, http://linkedlifedata.com/resource/umls/relation/R112169263, http://linkedlifedata.com/resource/umls/relation/R112169264, http://linkedlifedata.com/resource/umls/relation/R55131192, http://linkedlifedata.com/resource/umls/relation/R55131193, http://linkedlifedata.com/resource/umls/relation/R64674761, http://linkedlifedata.com/resource/umls/relation/R75939890, http://linkedlifedata.com/resource/umls/relation/R111823646, http://linkedlifedata.com/resource/umls/relation/R116364444, http://linkedlifedata.com/resource/umls/relation/R116364445, http://linkedlifedata.com/resource/umls/relation/R116364446, http://linkedlifedata.com/resource/umls/relation/R116364447, http://linkedlifedata.com/resource/umls/relation/R116364448, http://linkedlifedata.com/resource/umls/relation/R55131198, http://linkedlifedata.com/resource/umls/relation/R45128667, http://linkedlifedata.com/resource/umls/relation/R49118750, http://linkedlifedata.com/resource/umls/relation/R45060561, http://linkedlifedata.com/resource/umls/relation/R49118752, http://linkedlifedata.com/resource/umls/relation/R54941073, http://linkedlifedata.com/resource/umls/relation/R67558039, http://linkedlifedata.com/resource/umls/relation/R114287616, http://linkedlifedata.com/resource/umls/relation/R116314116, http://linkedlifedata.com/resource/umls/relation/R45440675, http://linkedlifedata.com/resource/umls/relation/R45440676, http://linkedlifedata.com/resource/umls/relation/R45440677, http://linkedlifedata.com/resource/umls/relation/R45440678, http://linkedlifedata.com/resource/umls/relation/R45440679, http://linkedlifedata.com/resource/umls/relation/R45440680, http://linkedlifedata.com/resource/umls/relation/R45440681, http://linkedlifedata.com/resource/umls/relation/R45440682, http://linkedlifedata.com/resource/umls/relation/R45440683, http://linkedlifedata.com/resource/umls/relation/R45440684, http://linkedlifedata.com/resource/umls/relation/R45726485, http://linkedlifedata.com/resource/umls/relation/R45726486, http://linkedlifedata.com/resource/umls/relation/R45726487, http://linkedlifedata.com/resource/umls/relation/R119278452, http://linkedlifedata.com/resource/umls/relation/R50969363, http://linkedlifedata.com/resource/umls/relation/R50969365, http://linkedlifedata.com/resource/umls/relation/R119278453, http://linkedlifedata.com/resource/umls/relation/R54944750, http://linkedlifedata.com/resource/umls/relation/R99579592, http://linkedlifedata.com/resource/umls/relation/R99579593, http://linkedlifedata.com/resource/umls/relation/R108100577, http://linkedlifedata.com/resource/umls/relation/R116326761, http://linkedlifedata.com/resource/umls/relation/R116326762, http://linkedlifedata.com/resource/umls/relation/R129810903, http://linkedlifedata.com/resource/umls/relation/R129810904, http://linkedlifedata.com/resource/umls/relation/R129810905, http://linkedlifedata.com/resource/umls/relation/R129810906, http://linkedlifedata.com/resource/umls/relation/R129810907, http://linkedlifedata.com/resource/umls/relation/R129810908, http://linkedlifedata.com/resource/umls/relation/R129810909, http://linkedlifedata.com/resource/umls/relation/R129810910, http://linkedlifedata.com/resource/umls/relation/R129810911, http://linkedlifedata.com/resource/umls/relation/R129810912, http://linkedlifedata.com/resource/umls/relation/R132463051, http://linkedlifedata.com/resource/umls/relation/R133684242, http://linkedlifedata.com/resource/umls/relation/R117990397, http://linkedlifedata.com/resource/umls/relation/R121662916, http://linkedlifedata.com/resource/umls/relation/R121662917, http://linkedlifedata.com/resource/umls/relation/R121662918, http://linkedlifedata.com/resource/umls/relation/R121567844, http://linkedlifedata.com/resource/umls/relation/R121567843, http://linkedlifedata.com/resource/umls/relation/R133620428, http://linkedlifedata.com/resource/umls/relation/R121567846, http://linkedlifedata.com/resource/umls/relation/R121567845, http://linkedlifedata.com/resource/umls/relation/R121662919, http://linkedlifedata.com/resource/umls/relation/R67549940, http://linkedlifedata.com/resource/umls/relation/R67519604, http://linkedlifedata.com/resource/umls/relation/R111410597, http://linkedlifedata.com/resource/umls/relation/R115854933, http://linkedlifedata.com/resource/umls/relation/R64653529, http://linkedlifedata.com/resource/umls/relation/R129131817, http://linkedlifedata.com/resource/umls/relation/R130123709, http://linkedlifedata.com/resource/umls/relation/R131191828, http://linkedlifedata.com/resource/umls/relation/R132930713, http://linkedlifedata.com/resource/umls/relation/R133942430, http://linkedlifedata.com/resource/umls/relation/R133942431, http://linkedlifedata.com/resource/umls/relation/R129131818, http://linkedlifedata.com/resource/umls/relation/R132930714, http://linkedlifedata.com/resource/umls/relation/R133942433, http://linkedlifedata.com/resource/umls/relation/R111800128, http://linkedlifedata.com/resource/umls/relation/R129131819, http://linkedlifedata.com/resource/umls/relation/R133942432, http://linkedlifedata.com/resource/umls/relation/R134162932, http://linkedlifedata.com/resource/umls/relation/R115855141, http://linkedlifedata.com/resource/umls/relation/R130123708, http://linkedlifedata.com/resource/umls/relation/R131191826, http://linkedlifedata.com/resource/umls/relation/R130899744, http://linkedlifedata.com/resource/umls/relation/R131191825, http://linkedlifedata.com/resource/umls/relation/R131191827, http://linkedlifedata.com/resource/umls/relation/R75937905, http://linkedlifedata.com/resource/umls/relation/R112415084, http://linkedlifedata.com/resource/umls/relation/R112415087, http://linkedlifedata.com/resource/umls/relation/R112844211