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skos:definition |
MSH: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.,CSP: 1,4-dihydro-2,6-dimethyl-4-nitrophenyl-3, 5-pyridine carboxylic acid methyl-2- methylphenylmethylaminoethyl ester; calcium channel blocker of the nifedipine family; used clinically as a cerebral and coronary vasodilator.,NCI: A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
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