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skos:definition |
MSH: Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive ionotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.,CSP: saturated, polymethylated naphthopyran which stimulates adenylate cyclase and so is used to probe cyclic AMP pathways; USP lists colfosin as antiglaucoma agent.
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