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rdf:type |
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MSH: A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.,CSP: beta-2 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia; it is proposed as a cardiotonic after myocardial infarction or open heart surgery.,NCI: A synthetic catecholamine with sympathomimetic activity. Dobutamine is a direct-acting inotropic agent and an adrenergic agonist that stimulates primarily the beta-1 adrenoceptor, with lesser effect on beta-2 or alpha receptors. Via beta-1 adrenoceptor of the heart, this agent induces positive inotropic effect with minimal changes in chronotropic activities or systemic vascular resistance. Dobutamine also causes vasodilation by stimulating beta-2 adrenergic receptors in blood vessels, augmented by reflex vasoconstriction resulting in increased cardiac output.
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skos:inScheme |
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skos:broader |
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R112185176,
http://linkedlifedata.com/resource/umls/relation/R32100786,
http://linkedlifedata.com/resource/umls/relation/R32100788,
http://linkedlifedata.com/resource/umls/relation/R44807545,
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http://linkedlifedata.com/resource/umls/relation/R32100796,
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http://linkedlifedata.com/resource/umls/relation/R32100789,
http://linkedlifedata.com/resource/umls/relation/R32100790,
http://linkedlifedata.com/resource/umls/relation/R32100793,
http://linkedlifedata.com/resource/umls/relation/R32100795,
http://linkedlifedata.com/resource/umls/relation/R32100791,
http://linkedlifedata.com/resource/umls/relation/R32100794,
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http://linkedlifedata.com/resource/umls/relation/R44807541,
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http://linkedlifedata.com/resource/umls/relation/R44807548,
http://linkedlifedata.com/resource/umls/relation/R44807549,
http://linkedlifedata.com/resource/umls/relation/R120269270,
http://linkedlifedata.com/resource/umls/relation/R120269271,
http://linkedlifedata.com/resource/umls/relation/R120269272,
http://linkedlifedata.com/resource/umls/relation/R120269274,
http://linkedlifedata.com/resource/umls/relation/R120269275,
http://linkedlifedata.com/resource/umls/relation/R120269276,
http://linkedlifedata.com/resource/umls/relation/R120269277,
http://linkedlifedata.com/resource/umls/relation/R120269278,
http://linkedlifedata.com/resource/umls/relation/R120269279,
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http://linkedlifedata.com/resource/umls/relation/R120269281,
http://linkedlifedata.com/resource/umls/relation/R120269283,
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http://linkedlifedata.com/resource/umls/relation/R120269287,
http://linkedlifedata.com/resource/umls/relation/R120269288,
http://linkedlifedata.com/resource/umls/relation/R120269289
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